The default behavior of the magic wand, smudge, blur, sharpen, paint bucket, clone stamp tool, and healing brush tool is to sample color only from pixels on the active layer. This means you can smudge or sample in a single layer even when other layers are visible, and you can sample from one layer and paint in another one.
Alternatively, you can choose to paint using sampled data from all visible layers. For example, you can use the clone stamp tool to clone an area containing pixels from all the visible layers.
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Adobe Photoshop can be a complex tool only because you can do so much with it, however for in this video series, we're going to keep it as simple as possible. In fact, in this video you'll see an overview of the few tools and Adobe Photoshop features we will use. When you see this video, you'll see how you can do so much with so few features, but you'll learn how to use them in depth in the future videos.