Before selecting a compression method, consider why you're using compression in the first place. If it is simply to save space on a disk during transfer to a client or printer, I recommend using no compression (None) at all. If you really need to save space, I find better results in using a program like WinZip or StuffIt to "pack" my files into small suitcases during travel. Then, they "unpack" without any compression adversely affecting the files themselves.
In the second area of the TIFF Options dialog box, specify the Byte Order. Then, if you plan to open this file in Adobe InDesign, for example, check the Save Image Pyramid option to save multiresolution information, allowing the file to be opened at varying resolutions.
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